Effect of Predictive Nursing Intervention on the Gastrointestinal Side Effects of I-131 Re-treatment in Patients with Differentiated Thyroid Cancer (DTC)

Abstract

Objective: The aim of this study was to explore the effect of predictive nursing intervention on the gastrointestinal side effects of I-131 re-treatment in patients with differentiated thyroid cancer (DTC). Methods: From January 2017 to August 2018, we invited patient with DTC who received I-131 re-treatment to enroll in this study. The participants were randomly assigned to control or predictive nursing intervention groups using a random number table. The primary outcomes were the incidence of gastrointestinal side effects and degree of patient satisfaction with respect to nursing. Patients in the intervention group received predictive nursing intervention, and patients in the control group received common nursing intervention. Result: A total of 69 patients were enrolled in the study. In patient characteristic, the gender, age and disease status were no significantly different for the participants in two groups. In addition, intervention group participants had less gastrointestinal side effect events, including nausea, vomiting and anorexia (10 vs 3, 8 vs 1, 12 vs 2). In nursing satisfaction assessment, intervention group participants provided better outcome in nursing satisfaction assessment compared with control group, that they provided most very satisfied assessment to predictive nursing intervention. Conclusion: Predictive nursing helped decrease the incidence of gastrointestinal side effects and improved patient satisfaction with nursing. Predictive nursing may be effective in DTC patients receiving I-131 re-treatment.