Effect of percutaneous nephroscopy combined with flexible ureteroscope on BMG and BUA of complex renal calculi and its clinical efficacy

Abstract

Objective To analyze the clinical effect and safety of percutaneous nephroscopy combined with soft ureteroscopy in the treatment of complicated renal calculi. Methods From January 2015 to October 2017, 120 cases of complicated renal calculi in our hospital were retrospectively selected. The patients in the control group were treated with minimally invasive percutaneous nephrolithotripsy and the patients in the observation group were treated with minimally invasive percutaneous nephrolithotomy combined with ureteral soft lithotripsy. The clinical effect of two groups was analyzed after treatment. Results Operation time, exhaust time, hospitalization time of the observation group were shorter than the control group, intraoperative bleeding was less than the control group (P 0.05). After the treatment, BMG, BUA, NGAL, Cys-C, hs-CRP, Ang I and Ang II levels of the observation group were lower than the control group (P<0.05), and the incidence of complications in the observation group was 8.33%, the control group was 21.67%, and the rate of complications in the observation group was lower than that of the control group (P<0.05). Conclusions Percutaneous nephrolithotomy combined with flexible ureteroscopy for the treatment of complex renal calculi can reduce blood loss, shorten hospitalization time, relieve stress reaction, and has little effect on renal function and safety. Key words: Kidney Calculi; Ureteroscopy; Nephrostomy, Percutaneous; beta 2-Microglobulin; Uric Acid