Abstract
Introduction Diabetes mellitus is a common metabolic disorder, characterized by hyperglycemia. T2DMwhich contributes major share of total diabetic population occurs due to diminished insulin secretion or insulin resistance. There is an increasing trend of diabetic population encompassing 108 mill
Highlights
Diabetes mellitus is a common metabolic disorder, characterized by hyperglycemia
N=6; values expressed as Mean ± SD, Data analyzed by one way ANOVA test with Bonferroni's test,$ indicates p value
This study showed that petroleum ether extracts of P.murex dry seed (PEPM) alone as well as in combination with metformin, decreased the testicular tissue MDA level and increase in SOD activity significantly against disease control and similar to that of normal control / metformin
Summary
Diabetes mellitus is a common metabolic disorder, characterized by hyperglycemia. T2DM which contributes major share of total diabetic population occurs due to diminished insulin secretion or insulin resistance. There is an increasing trend of diabetic population encompassing 108 million in 1980 to 422 million in 2014.The prevalence of diabetes among adults e”18 years of age has been increased from 4.7% in 1980 to 8.5% in 2014. An estimated 1.5 million deaths in 2012 were directly caused by diabetes whereas another 2.2 million deaths contributed by high level of blood glucose. WHO projects that in 2030 diabetes will be the 7th leading cause of death[1].
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