Abstract
Background: Parathyroid dysfunction leading to symptomatic hypocalcemia is not uncommon following a total or completion thyroidectomy and is often associated with significant patient morbidity and a prolonged hospital stay. The current study is designed to evaluate the role of parathormone (PTH) levels detected in a standard time frame after total thyroidectomy as a predictor of post-thyroidectomy hypocalcemia. Objectives: To investigate whether postoperative parathyroid hormone level is a parameter to identify hypocalcemia after total thyroidectomy as well as to find out the optimum cut-off value of parathyroid hormone in early postoperative period. Methodology: This was a cross-sectional study. A total of 103 patients’ male-female with a variety of thyroid disorders with an indication of total thyroidectomy attended the outpatient department and inpatient department of Surgery and Otolaryngology, BSMMU. This study was carried out from March 2018 to September 2019. The routine clinical assessment and the preoperative laboratory investigations were performed before operation. Preoperative levels of serum PTH were measured. Statistical analysis was carried out using SPSS version.22.0. Results: The levels of PTH in the immediate postoperative period showed that 17(16.50%) patients belonged to low PTH (<14). The mean PTH in immediate post-operative was 36.79±21.71 with a range from 0.2 to 111.3. Regarding the distribution of the study patients by serum calcium, it was observed that 20.39% of patients belonged to low (<8 mg/dl) serum calcium. The mean serum calcium level was 8.47±1.19 with ranging from 2.1 to 10.6. In the current study, the scatter diagram showed a positive significant correlation (r=0.310; p=0.001) between PTH and S. Calcium immediate post-operative period. ROC curve for finding the cut-off value of PTH in the immediate post-operative period to predict hypocalcemia among the study population. Conclusion: Hypocalcaemia after the total or completion ....
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