Abstract
The effects of parathyroid extract (PTE) on the incorporation of subsequently injected P32 into various phosphate fractions of the rat kidney were investigated: total phosphate, acid-soluble phosphate, inorganic phosphate, acid-soluble organic phosphate, phospholipid and nucleic acid phosphate. For further delineation of the hormone’s effects, fractionation of acid-soluble phosphate compounds by a Dowex 1 formate column and paper chromatography of phospholipids were also carried out. Incorporation of P32 in each phosphorus fraction separated was, in nearly every case, higher in the PTE group than in the saline control group. The greatest hormonal stimulation was observed in the phospholipid fraction. When PTE was given intravenously to rats 15 min after P32 injection, the relative specific activity in all fractions increased sharply 7 min later. Further fractionation of acid-soluble phosphate showed a higher incorporation of P32 in essentially all fractions of phosphate in the hormone-treated groups. The ...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
