Effect of negative emotions on quality of life of patients with advanced non-small cell lung cancer in palliative treatment

Abstract

Objective To explore the influence of negative emotions of patients with non-small cell lung cancer on quality of life in palliative treatment. Methods 120 patients with non-small cell lung cancer diagnosed in our hospital from January 2013 to February 2015 were selected as the observation group.At the same time, 100 cases of healthy persons were selected as control group.The anxiety self rating scale (SAS), depression self rating scale (SDS) and the questionnaire of life quality core scale score were recorded.The correlation between negative emotions and quality of life was analyzed. Results The scores of SDS and SAS in control group were 27.53±9.42 and 31.29±7.50, while they were 38.34±8.63 and 37.32±7.59 in observation group respectively, there was statistical significance between the two groups(t＝8.87，5.90，respectively，all P<0.05)．The overall quality score in observation group was 60.52±12.39，which was in a poor level.The negative emotions of observation group were negatively correlated with the total quality and function score (r＝－0.66-－0.29，all P<0.05)，but were positively correlated with symptom score (r＝0.33-0.60，all P<0.05)．Logistic multivariate analysis showed that depression (β＝1.730，OR＝5.642)，anxiety (β＝2.150，OR＝8.588) and other negative emotions seriously affected the quality of life of the observation group. Conclusions Negative emotions seriously reduce the quality of life in the palliative treatment of patients with advanced non-small cell lung cancer，the timely discovery and intervention on depression，anxiety status of the patients is very important to improve the life quality of patients. Key words: Negative emotions; Non-small cell lung cancer; Quality of life