Abstract
A single intraperitoneal injection of lipopolysaccharide Coli026:B6 caused pronounced changes in the lungs of rats a day later: massive lymphoid peribronchial infiltration, an increase in the volume density of interalveolar connective tissue, the number of macrophages in it. Intragastric administration of the medication containing esinochrome, tocopherol and ascorbic acid, preceding the introduction of lipopolysaccharide, significantly reduced the severity of pathological changes in the lungs that develop under its influence.
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