Abstract

Objective To study the effect of lung surfactant and high-frequency oscillatory ventilation in treating neonatal respiratory distress syndrome. Methods 82 cases of neonatal respiratory distress syndrome from January 2012 to March 2016 were selected and divided into conventional ventilation group (n=41) and high-frequency oscillatory ventilation group (n=41). The clinical symptoms, blood gas analysis, cure rate, the computer time, length of hospital stay, and complications were compared. Results After treatment 1 h, 6 h, 12 h, 24 h, PaO2 in high-frequency oscillation ventilation group was higher than that in conventional ventilation group (all P 0.05). Conclusions Lung surfactant and high-frequency oscillatory ventilation can improve the blood gas analysis and oxygenation index, shorten the mechanical ventilation treatment time and hospital stay, is worth application. Key words: Lung surfactant; High-frequency oscillatory ventilation; Neonatal respiratory distress syndrome

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