Abstract
Addition of Laticauda semifasciata venom to the outside bathing solution of isolated frog skin elicited sustained increases in transepithelial potential difference, short-circuit current and transepithelial electrical resistance. The Laticauda semifasciata venom-induced short-circuit is carried by a net active Na + transfer from the outside to the inside bathing solution while the increase in transepithelial resistance is accounted for by a decrease in the outside to inside Cl − flux.
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