Effect of laparoscopic ovarian transposition before radiotherapy on ovarian reserve function in young patients with cervical cancer

Abstract

Objective To study the effect of laparoscopic ovarian transposition before radiotherapy on ovarian reserve function in young patients with cervical cancer. Methods Thirty-two young patients with cervical cancer were selected as the observation group, and they were treated by radical hysterectomy combined with ovarian transposition and postoperative radiotherapy. Another 32 patients with cervical cancer who were treated by radical radiotherapy in the same period were selected as the control group. The sex hormone levels and ovarian reserve function were compared between the two groups. Results After treatment, the levels of follicle stimulating hormone and luteinizing hormone and rate of ovarian reserve function failure in the observation group were(9.1±2.5)U/L, (15.7±5.6)U/L, 31.3%, which were significantly lower than those in the control group [(106.3±36.3)U/L, (64.5±26.2) U/L, 75.0%, P<0.05]. Conclusions Laparoscopic ovarian transposition can reduce the effect of radiotherapy on ovarian reserve function and endocrine function in young patients with cervical cancer. It can help keep certain ovarian function, and it is worth to be applied and popularized in clinic. Key words: Cervical cancer; Ovarian transposition; Radiotherapy