Effect of Jiuwei Jiangzhi tablet on liver homogenate in rats with hyperlipidemia model

Abstract

To observe the effect of Jiangzhi tablet on liver homogenate of hyperlipidemia model rats, seventy-two rats were randomly divided into 6 groups: blank control group, model group, Xuezhikang group and Jiangzhi tablet group. Except for the blank group, the rats were fed with high fat diet and the compound factors of intragastrically fat milk to establish hyperlipidemia model. The corresponding drugs were given intragastrically for 21 days in each administration group, and the eyeballs were removed 2 hours after administration on the 21st day, and the whole blood viscosity was measured. The rats were killed, the liver was taken, and the content of TC,TG in liver homogenate was measured. Hyperlipemia model rats were successful in the replication. Compared with the model group, the levels of TC and TG of the liver homogenate (P <0.01) could be significantly reduced in the high, middle and low dose lipid-lowering tablet groups. Jiangzhi tablet can significantly reduce blood lipid and regulate lipid metabolism in rats with hyperlipidemia.