Abstract
Male rats treated with 100 mg/kg for 60 days of isolated fractions of the Barleria prionitis root methanolic extract (Fr. I and Fr. II) showed a significant reduction on spermatogenesis without affecting general body metabolism. Sperm motility as well density in cauda epididymides was reduced significantly. The fertility was decreased by 33.4% in Fr. I and 100% in Fr. II treated rats. The blood parameters were within the normal range. Total protein, glycogen and sialic acid contents of testes were reduced after the plant fractions treatment. Seminal vesicular fructose was decreased significantly after the treatment. The population of various spermatogenic cells such as primary spermatocytes, secondary spermatocytes and round spermatids were declined significantly in Fr. II treatment groups whereas in Fr. I treated animals preleptotene spermatocyte and spermatid number was decreased. There was no significant change in the number of Sertoli cells and spermatogonia in any of the treatment group.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
