Abstract
Background People living with Type 2 diabetes mellitus with comorbid depression have increased chances of poorer outcomes in terms of glycaemic control or medication adherence and even quality of life.Objective The present study aimed to estimate the effect of intervention on glycemic control among adult population with Type 2 diabetes mellitus and comorbid depression who had received either treatment with an antidepressant medication ADM or a psychotherapeutic intervention like cognitive-behavioural therapy CBT. Methods The study was carried out at a tertiary care teaching hospital in Central Karnataka. The study participants were adult patients 30ndash70 years with type 2 diabetes mellitus of over 12-month duration with no prior history of psychiatric illnesses or intake of anti-depressants. Data was collected using a pre-tested semi-structured questionnaire.Results In the post-intervention phase the participants who received cognitive-behavioral therapy CBT had significantly lower depression scores on the Montgomery and Asberg Depression Rating Scale MADRS when compared to subjects who were on antidepressant medication ADM 95 CI -10.068 to -9.606 p lt0.0001. Similarly in terms of diabetes control the participants who received CBT had better glycemic control as measured by HbA1c levels compared to those who received ADM 95 CI -1.4632 to -0.5108 p lt0.0001.Conclusion In patients with diabetes with comorbid depression interventions to treat depression could improve diabetes care. Overall these results suggest that a behavioural intervention for depression is effective for managing depression and improving glycemic control in adults with type 2 diabetes.
Published Version
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