Abstract
The present study was designed to investigate the effect of different concentrations of Maxxthor on somehematological and oxidative stress parameters in male albino rats.Twenty male rats with age of 6-8 weeks andweight of 200-250gm were equally divided into four groups as follow:G1 treated with normal saline as controlgroup,while G2,G3andG4groups were treated with(0.01,0.1,1)mg\kg body weight of Maxxthor respectivelyfor 40 days.The following hematological parameters were measured: red blood cell(RBC),hemoglobin(Hb),white blood cell(WBC), platelets(PLT),malondialdehyde(MDA),glutathione(GSH),catalase andvitamin E. The hematological parameters results revealed highly significant(p<0.01)decreasein RBC andH,while a highly significant(p<0.01)increase in WBC and PLT in all treated groups as compared with control.The oxidative stress parameters results revealed highly significant(p<0.01)increase in MDA level,whilehighly significant(p<0.01)decrease in GSH,catalase and vitamin E level were noticed in all treated groupsas compared with control .
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