Abstract
Abstract—Rats were exposed to air containing I2131 and I2127 in various ratios. In the virtual absence of I2127 the maximum levels of I131 in the thyroids were 20 per cent of the total I131 deposited in rats on a diet normal in iodine and 40–50 per cent in rats on a low-iodine diet. Maximum depression of I131 uptake in the thyroid, 0.05 per cent of the total deposited, was obtained at the highest levels of I2127, 5 mg/l, air, which approached the toxic limit. These levels of uptake were roughly equivalent to those obtained when rats were given 100 mg KI subcutaneously prior to exposure to I2131. Dilution of I131 vapor with stable iodine was much less effective in reducing the thyroid uptake of I131 in dogs. Inhalation of 50 mg I2137 reduced the thyroid uptake by about one-half.
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