Abstract
The contents of epinephrine and norepinephrine in the salivary glands, oral, esophageal, and gastric mucosa, and in the blood after parenteral injection of epinephrine measured by high-performance liquid chromatography. It is shown that 1.5 h postinjection the content of epinephrine in all studied organs and in the blood considerably surpassed the initial level, while the content of norepinephrine sharply decreased in the mucosa and increased in the blood. It is suggested that under conditions of hyperadrenalinemia, receptory binding of epinephrine far surpasses that of norepinephrine, attesting to a competition between these catecholamines for receptors on epitheliocytes which depends on their concentration in different body fluids.
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