Abstract
Hydroxyurea inhibits mitotic activity in cells of the antheridial filaments of <i>Chara vulgaris</i> by blocking phase S and phase G<sub>2</sub>. Blocking of cells in phase G<sub>2</sub> also occurs in the case of the root meristem cells of <i>Helianthus annuus</i> and <i>Vicia faba</i> var. <i>minor</i>. <sup>3</sup>H-thymidine incorporation confirmed autoradiographically the blocking of cells of the antheridial filaments in <i>Chara vulgaris</i> at phase S and slowing down of the rate of DNA replication. Incubation with <sup>3</sup>H-phenylalanine demonstrated that hydroxyurea inhibits protein synthesis.
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