Abstract
目的 探讨儿童上消化道疾病幽门螺杆菌(Helicobacter Pylori,HP)感染率及HP感染对儿童缺铁性贫血(Iron Deficiency Anemia,IDA)的影响.方法 2000年6月至2004年6月本院住院及门诊335例患者上消化道疾病患儿,其中缺铁性贫血患儿109例;采用奥林巴斯GIF-V电子胃镜检查,并进行快速尿素酶试验,14C呼气试验检测;随机选择HP感染阳性和阴性患儿各50例检测血清铁蛋白(SF)、血红蛋白(Hb)、平均红细胞体积(MCV)、红细胞分布宽度(RDW).结果胃镜检查检出HP感染61例,检出率占18.2%(61/335).各年龄组胃十二指肠疾病HP感染率具有显著差异(P＜0.05),HP感染与年龄呈显著正相关(r=0.749,P=0.003),随着年龄的增长,上消化道疾病的发生率逐渐升高(P＜0.05),消化性溃疡的发生率也随年龄增长而增加(十二指肠溃疡:r=0.726;胃溃疡:r=0.703;P＜0.05).HP感染阳性组与阴性组比较SF、Hb、MCV、RDW差异均有显著性意义(P＜0.05);感染Hp儿童血清铁蛋白水平明显低于未感染Hp儿童.结论小儿HP感染随年龄增长而增加,HP感染儿童机体铁营养水平降低,是造成或加重儿童机体铁营养不良的独立危险因素,HP感染是IDA的原因之一,在治疗IDA的过程中应注意清除Hp感染。
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
