Effect of health education to nucleotide drugs therapy in patients with HBV genotypes influence

Abstract

Objective To explore the nursing methods for nucleotide drugs therapy in patients with hepatitis B virus (HBV) genotypes,and improve their quality of life and prolong survival time.Methods By using prospective cohort study of clinical research methods,from June 2010 to June 2012,260 cases of chronic viral hepatitis b,were randomly divided into lamivudine and adefovir group (all 100 cases) and control group (60 cases),the former two groups used pyrophosphoric acid sequencing method in antiviral treatment before and after all testing HBV genotype and drug resistance genes,follow-up tracking for 72 weeks,no follow-up and related inspection in control group.According to the selected drugs by professional personnel responsible for providing holistic nursing care and the drug supervision,all patients were given targeted health education,with the follow-up and medication guide.Results Through the doctors or the nurses' targeted guidance and health education,the medication time and the mastering level to medicines effect in observation group improved more obviously than control group,for 100％;but not for health education of controls,withdrawal or without authorization by the proportion of dressing up to 15％.Conclusion Nucleotide drugs for HBV can cause a population,drug resistance during treatment with drugs to the nursing instruction and health education are very important to improve the patients' behavior of following doctors'instruction. Key words: Nucleotide drugs; Hepatitis B; Nursing