Effect of Guava (Psidium guajava) Leaves Essential Oil on Some Reproductive Parameters in Male Guinea Pig (Cavia porcellus)

Ngoula Ferdinand ,Nouboudem S Christiane ,Tadondjou Cyril D’alex ,Kouam Jean-Marc ,Tsafack Borice ,Ngoumtsop Victor Herman ,Kana Jean Raphaël ,Augustave Kenfack ,Pièrre Kamtchouing ,Nguemdjo T Maryvone ,Akassa Herman ,Ousmane Issa Abdel Djalil ,Marco Galeotti ,J Tchoumboué

doi:10.4172/2329-6577.1000125

Ngoula Ferdinand , Nouboudem S Christiane + Show 12 more

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https://doi.org/10.4172/2329-6577.1000125

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Abstract

Aim: To assess the effects of essential oil from guava leaves on some reproductive parameters. Methods: Thirty-two male guinea pigs (Cavia porcelus) of three months old and weighing between 350 and 400 g were used. These guinea pigs were divided into 4 groups of 8 animals each. Each group was randomly attributed orally for 60 days one of the following guava leaf essential oil doses: 0 (control group), 80, 100 and 120 μl of oil per kg body weight. At the end of treatment, all animals were sacrificed to assess the reproductive parameters. Results: Body weight, relative weight of the seminal vesicles, vas deferens, and epididymis were not significantly increased (p>0.05) with the considered guava leaves essential oil doses. The testes weights significantly increased (p<0.05) in animals who received 100 and 120 μl/kg body weight compared to control. A significant increase (p<0.05) in sperm concentration, mobility and viability was observed in animals which received the essential oil doses compared to control. Also, the level of proteins and testosterone in serum and testes significantly increased (p<0.05) with the essential oil doses. Conclusion: Guava leaves essential oil can be used to improve male reproductive performances.

Highlights

IntroductionEssential oil (or sometimes vegetable gas) is the concentrate and hydrophobic liquid of volatile aromatic compounds (odoriferous) of a plant
Essential oil is the concentrate and hydrophobic liquid of volatile aromatic compounds of a plant
Administration of guava leaves essential oil for 60 days significantly increased the epididymal sperm count dose-dependently compared to the control group

Summary

Introduction

Essential oil (or sometimes vegetable gas) is the concentrate and hydrophobic liquid of volatile aromatic compounds (odoriferous) of a plant. It is specific to seed coniferous plants and is found in the families of Labiatae and Myrtaceae [1]. The essential oils have some common points in their modes of action, their properties are varied: they are anti-infectious, antifungal, antiparasitic, antibacterial, antiinflammatory, etc. These properties are used in animal production [1,2]. Guava (Psidium guajava) is a fruit tree of the family of Myrtaceae, native from South America and growing in the tropics. Studies on extracts from the leaves of P. guajava and essential oil they contain showed that they possess anti-inflammatory, antibiotics, analgesics, hepato protective and antioxidant activities [68]

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