Abstract
In recent years, commercial glyphosate herbicide formulations have been widely used in agriculture to control aquatic and terrestrial weeds. These pesticides may result in disruption of ecological balance, causing damage to nontarget organisms, including fish. Carassius auratus L. specimenes were exposed to glyphosate herbicide in concentration of 2.5mg/L and, respectively, 5 mg/L for 120 h, in laboratory condition. Thus, the effects of this chemical agent on both hematological parameters (hemoglobin, hematocrit, number of red blood cells) and on oxidative status indices (SOD, CAT, GPX, MDA) at Prussian carp experimental lots were analyzed. Our results showed, in comparison with the reference batch, the influence of glyphosate on the analyzed hematological and biochemical parameters, in close correlation with the administered pesticide dose.
Highlights
In recent years, commercial glyphosate herbicide formulations have been widely used in agriculture to control aquatic and terrestrial weeds
In comparison with the reference batch, the influence of glyphosate on the analyzed hematological and biochemical parameters, in close correlation with the administered pesticide dose
Considering that the evaluation of fish blood parameters could be a useful tool to understand the impact of herbicide and pesticide chemical compounds on population health, a first objective of our study was the determination of hematocrit, hemoglobin and red blood cells in the experimental groups of Carassius auratus
Summary
Commercial glyphosate herbicide formulations have been widely used in agriculture to control aquatic and terrestrial weeds These pesticides may result in disruption of ecological balance, causing damage to nontarget organisms, including fish. Glyphosate [N-(phosphonomethyl) glycine] is a broad spectrum herbicide, being commonly used in agriculture, and in other non-agricultural areas to stop the growth and development of undesirable terrestrial and hydrophilic plants [7,8,9] It seems that, it’s possible mechanism of action is to inhibit 5-enolpyruvylshikimate3-phosphate synthase involved in the shikimate pathway, the metabolic pathway present in plants and microorganisms, but absent in animals, which is why, for years, this herbicide was considered to be non-toxic or relatively low toxicity for animal organisms, relatively recent data pointing to an increased rate of bioaccumulation, resulting in intoxication phenomena and the risk of affecting the physiological-normal state [1012]. The goal of this study was to evaluate the toxic potential of glyphosate at concentrations of 2.5 mg/L and 5 mg/L, respectively, after 120 h exposure to Carassius auratus L
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
