Abstract
Effect of Ginger and curcum powder on fatty liver in Male Albino Rats intoxicated with oxytetracycline
Highlights
Liver is an important digestive organ, and closely connected to inflammation, which is the innate defense system of the body for removing harmful stimulus (Lam et al, 2016)
NAFLD comprises a wide spectrum of hepatic damage, from simple steatosis alone, to inflammatory changes found in nonalcoholic steatohepatitis (NASH) and advanced fibrosis and cirrhosis of the liver
The mean values of body weight gain (BWG %); feed intake (g/day for each rat) and feed efficiency ratio (FER) of rats fed negative control group, positive control group; fatty liver group {oxytetracycline injection (120mg/kg body wt.) for three days respectively} fed on basal diet containing ginger and curcum powder at 2.5% & 5% in groups {which fed on basal diet containing ginger and curcum powder at 2.5% & 5% & injected with oxytetracycline after 28 days for three days respectively, were investigated and summarized in Tables ( 1 )
Summary
Liver is an important digestive organ, and closely connected to inflammation, which is the innate defense system of the body for removing harmful stimulus (Lam et al, 2016). Nonalcoholic fatty liver disease ( NAFLD ) has become a major public health hazard worldwide. Helal et al, (2012) showed that the prevalence of NAFLD has apparently increased in proportion to the increasing incidence of obesity in both adults and children. Ginger belongs to family Zingiberaceae, it’s widely used as a food additive and coloring agent. It is one of the most commonly used spices around the world. Curcum is a rhizomatous perennial herb that belongs to family Zingiberaceae. It is a tropical plant and is the source of the spice turmeric, which is derived from the dried, ground rhizome. Antitumor, antimicrobial, anti-inflammatory, wound healing, lipid-reducing, chemopreventive, immunomodulatory, and gastroprotective activities and all these are documented by Maizura et al, (2011) and Nwozo et al, (2014)
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