Abstract
The influence of a homologous gamma interferon preparation (MuIFN-gamma) on in vitro spreading of freshly-seeded unelicited mouse peritoneal macrophages (MPM) was tested. Light microscopy and scanning electron microscopy observations gave comparable results. Addition of MuIFN-gamma enhanced the spreading on solid surfaces, especially 3-5 hours after seeding. Maximal effect was achieved with 10 units of IFN. Addition of specific anti-MuIFN-gamma or treatment of the preparation at pH 2 eliminated both antiviral activity and effect on spreading of MPM.
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Schedule a callMore From: Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology
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