Abstract

This study aimed to investigate the effect of a fluoride varnish with added casein phosphopeptide-amorphous calcium phosphate treatment on the prevention of enamel erosion, and it compared the results with those of other fluoride varnishes. Fifty enamel specimens obtained from bovine incisors were randomly divided into five groups (n = 10) based on the type of surface pretreatment used: intact enamel (Group 1); intact enamel+erosive cycles (Group 2); intact enamel+MI varnish+erosive cycles (Group 3); intact enamel+Clinpro White varnish+erosive cycles (Group 4); and intact enamel+Duraphat varnish+erosive cycles (Group 5). The specimens were subjected to erosive cycles for five days. The surface roughness was evaluated using atomic force microscopy. The results were statistically analyzed using one-way ANOVA and Tukey's tests. Group 1 had the smoothest surfaces. After the erosive cycles, the greatest surface roughness values were observed in Group 2, followed by Groups 5, 4, and 3, respectively. Statistically significant differences were observed among all groups (p < 0.05). The application of fluoride varnishes had some positive effects on preventing enamel erosion; however, the most effective agent was fluoride varnish with added casein phosphopeptide-amorphous calcium phosphate.

Highlights

  • Dental erosion is defined as an irreversible loss of dental hard tissues by the chemical dissolution process initiated by acids of nonbacterial origin or chelation when the surrounding aqueous phase is undersaturated with respect to tooth mineral [1, 2]

  • Products based on calcium and phosphate can be an alternative for preventing tooth enamel erosion [12,13,14,15,16,17,18]

  • Two null hypotheses tested were as follows: (1) fluoride varnish containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) does not increase the enamel’s resistance to erosion and (2) there are no significant differences in the prevention of enamel erosion among different types of fluoride varnish treatments

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Summary

Introduction

Dental erosion is defined as an irreversible loss of dental hard tissues by the chemical dissolution process initiated by acids of nonbacterial origin or chelation when the surrounding aqueous phase is undersaturated with respect to tooth mineral [1, 2]. To prevent the occurrence of dental erosion, resources for diet guidelines may be used, as well as the application of products that minimize demineralization and promote remineralization of the tooth structure [4]. Products based on calcium and phosphate can be an alternative for preventing tooth enamel erosion [12,13,14,15,16,17,18]. Administered casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) buffers free calcium and phosphate ion activity, maintaining a state of supersaturation with respect to tooth enamel that helps prevent demineralization and facilitates remineralization on dental caries or erosion [19]

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