Abstract
PurposeThe purpose of this paper is to evaluate safety of the enzymatic treatment (garlic peroxidase) for removing aflatoxin B1 (AFB1) from foods.Design/methodology/approachAn in vivo study was carried out on male wistar rats for three weeks. Since AFB1 is a hepatotoxic; the effect of AFB1 and the enzymatic detoxification of AFB1 on the liver function was studied by determining the serum activities of various hepatic enzymes in different groups of experimental rats.FindingsThe peroxidase (POD) isolated from garlic possess AFB1 degrading properties and the overall detoxification is safe to be used in various foods/feeds as the reaction products produced no toxicity in the adult male wistar rats. Rats fed with aflatoxin contaminated diet possessed increased activities of all the hepatic enzymes investigated; showing symptoms of liver damage compared to rats fed with enzyme treated diet.Practical implicationsThe results of this study can be utilized for commercialization of the garlic POD mediated AFB1 detoxification from feeds/foods.Originality/valueThe aflatoxin detoxyfying abilities of garlic POD and its in vivo safety studies have not been reported so far.
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