Abstract
Folic acid deficiency was induced in rats by feeding folate deficient diet containing normal (35 mg iron/kg diet) or marginal amounts (20 mg iron/kg diet) of iron. The effect of excess iron intake on liver folate repletion following supplementation with folic acid was studied. Large quantities of iron supplements (210 mg iron/kg diet) had no adverse effect on liver folate repletion. On the other hand the replenishment of liver folate reserves was better with excess iron intake.
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