Effect of different time to milk on very low birth weight premature infants

Abstract

Objective To discuss the effect of milking in different times on very low birth weight premature infants .Methods Totals of 78 very low birth weight premature infants were chosen and divided into the no asphyxia group A（Apgar score 7-10）, mild asphyxia group B（Apgar score 4-6.9）, sever asphyxiation group C（Apgar score 0-3.9） according to the Apgar score.Then every group was randomly divided into the subgroups：13 neonates for group A1, group A2, group B1, group B2, group C1 and group C2.Group A1, group B1 and group C1 added early trace formula into enteral feeding in 24 hours until converted to full-intestinal absorption, while group A2 , group B2 and group C2 were given the same nutrition after 24 hours.Changes of indicators of infants were observed in all groups .Results The weight gain , excrement , time to regain body bass, PPN time, FEN time and hospitalization day was respectively （17.5 ±6.6） g/d,（3.2 ±1.2） times/d, （4.7 ±2.6）d, （9.2 ±4.1）d, （20.4 ±7.1）d ,（25.6 ±4.8）d in group A1, and（11.4 ±5.3）g/d, （1.9 ± 1.7）times/d, （6.2 ±3.1） d,（13.1 ±3.7） d,（25.1 ±7.9） d and（29.7 ±5.3） d in group A2, and the differences were statistically significant （ t =7.045,5.379,6.001,5.891,5.913,7.704, respectively;P 〈0.05）.The weight gain, excrement, time to regain body bass, PPN time, FEN time and hospitalization day was respectively （10.0 ±3.5） g/d,（1.4 ±0.8） times/d,（7.9 ±3.7） d, （15.6 ±5.2） d, （27.7 ±6.8） d, （32.8 ±8.2）d in group B1, and（10.6 ±2.8）g/d,（1.3 ±1.1）times/d,（8.1 ±3.1）d,（14.8 ±6.1）d, （28.1 ±5.4）d,（36.4 ±8.7）d in group B2, and the differences were not statistically significant （t=1.964, 1.157,2.131,1.467,2.003,1.980, respectively;P〉0.05）.The weight gain, excrement, time to regain body bass, PPN time, FEN time and hospitalization day was respectively （4.4 ±1.8） g/d,（0.0 ±0.3） times /d, （13.4 ±4.8）d, （19.2 ±7.7）d, （36.1 ±9.5）d,（43.5 ±10.2）d in group C1, and （7.4 ±3.4）g/d,（1.1 ± 0.9）times/d,（10.6 ±3.1） d,（17.0 ±6.9） d,（30.2 ±7.5） d and（39.9 ±9.1） d in group C2, and the differences were statistically significant （ t =5.549,6.000,5.836,5.907,8.114,7.908, respectively;P 〈0.05）.There was statistically significant difference of gastrointestinal functional damage between group A 1 and A2（χ2 =8.496,P〈0.05）.There was no statistically significant difference of gastrointestinal functional damage between group B1 and B2 （χ2 =2.001,P〉0.05）.There was statistically significant difference of gastrointestinal functional damage between group C1 and C2 （χ2 =13.457,P 〈0.01）.Conclusions Presence of asphyxia hazard is one of the most important standards of starting breastfeeding in 24 hours for very low birth weight premature infants , and Apgar score can be used as one of the references for start milking for premature infants . Key words: Infant,low birth weight; Feeding intolerance; Music therapy; Touch therapy; Non-nutritional sucking method