Effect of different hypercapnic-hypoxic training protocols on the arterial pressure levels in hypertensive patients

Abstract

In order to evaluate different hypercapnic-hypoxic training protocols effect on the arterial pressure levels in hypertensive patients we studied 60 patients (mean 49,5±2,7 yrs old) with mild essential hypertension (EH). Hypercapnic-hypoxic training protocols were based on measured breathing exercises with different length of breathing phases: inhalation, exhalation, holding patients breath, and were administrated under the control of oxygen and carbooxigen blood pressure, exhaled air gases chronometric analysis, individual patients perceptibility to the hypercapnia and hypoxia levels. All patients were randomized depending on the exhaled air levels of CO2 and O2: in the 1st group CO2-5,2%, O2-14,6%; in the 2nd group CO2-5%, O2-14,9%; in the 3rd CO2-4,7%, O2-15,1%; in the 4th CO2-4,1%, O2-16,4%. These levels of CO2 and O2 were safe to use them in essential hypertension rehabilitation protocol. Patients fulfilled hypercapnic-hypoxic training protocols everyday by 30-40 min, 3 times per day, 6-8 weeks. After hypercapnic-hypoxic training rehabilitation course endpoint decreasing of systolic and diastolic blood pressure (SBP, DBP) was gained: in the 1st group SBP decrease was 16,7% (p<0,05), DBP-9,1% (p<0,05); in the 2nd group SBP reduce was 14% (p<0,05), DBP-7,2% (p>0,05); in the 3d group SBP decreased for 12% (p<0,05), DBP for 6% (p>0,05); in the 4th group SBP reduced for 10,3% (p>0,05), DBP for 5,4% (p>0,05). Thus, using of measured hypercapnic-hypoxic breathing training rehabilitation protocol in patients with mild essential hypertension lead to reducing of high blood pressure indexes.