Abstract
Se metabolism in lambs was studied following Se supplementation at different levels. For 3 months, four groups of lambs were fed a basal diet containing 0.082 mg Se/kg DM (A) or the same diet plus a mineral mixture with selenite providing 0.25, 0.41 or 0.58 mg Se/kg DM (B, C and D, respectively). Se concentration in whole blood and glutathione peroxidase (GSH-Px) activity in red cells of Se-treated lambs increased during the time of experiment. Plasma Se concentration in all groups reached a plateau (2-times the initial value) after 1 month. Although plasma GSH-Px activity increased with time in Se-treated lambs, there were only slight, but not significant, differences between groups B, C and D. It was concluded that dietary Se levels of 0.25 mg/kg DM are sufficient to cover requirements of blood components for maintaining plateaus of Se concentration and GSH-Px activity in lambs.
Published Version
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