Effect of Dietary Lipids and Cholesterol on the Levels and Synthesis of Some Hepatic Lipid Components of Young Chickens

Abstract

INTRODUCTIONSEVERAL workers (Ridout et al., 1952; Klein, 1958; Morin et al., 1962; Diller et al., 1961) have reported that dietary cholesterol increased liver glyceride, cholesteryl ester and to a lesser extent, free cholesterol. Liver cholesterol increased to the same extent when cholesterol was consumed with unsaturated or saturated fat (Homer et al., 1960). Unsaturated fat stimulated the incoporation of labeled acetate into liver (Wood and Migicovsky, 1958; Weiss et al., 1967), whereas triglyceride radioactivity decreased and with no change in cholesteryl ester (Weiss et al., 1967).This study is concerned with the changes in the levels and synthesis of lipid fractions of liver of young chickens on a saturated or unsaturated diet with or without cholesterol. The results obtained demonstrate that chicken liver responds to the ingestion of cholesterol differently, depending on the type of fat consumed.MATERIALS AND METHODSA total of 45 newly-hatched New Hampshire chickens, from…