Abstract
This study was undertaken to determine the effects of Deltamethrin and Ridomil, singly and in combination, on epididymal sperm parameters and reproductive hormone levels of male rats. Thirty two albino rats were divided into four independent treatment groups; A, D, R and C. Group A was the control and did not receive any pesticide treatment. Groups D (100 mg of Deltamethrin/kg body weight), R (100 mg of Ridomil/kg body weight) and C (50 mg Deltamethrin+50 mg Ridomil/kg body weight) received pesticide treatment at forty eight hour intervals for nine weeks, via direct mixing in the animal ration. After nine weeks the animals were sacrificed, blood was collected and epididymal sperm parameters were assessed. Significant (P<0.001) decreases were observed in sperm count and sperm motility between the control and groups D and C. Sperm viability, sperm head abnormality and pH of semen did not reveal any significant differences (P<0.05). Follicle stimulating hormone and luteinizing hormone showed significant (P<0.01) decreases in groups D and C, but no significant differences were observed in testosterone levels. Deltamethrin, and Deltamethrin+Ridomil combination decreased sperm count, sperm motility, and serum gonadotropins of the rats.
Published Version
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