Abstract
Abstract Background: The aim of the present study was to determine the action of crude latex from Euphorbia tirucalli dissolved in DMSO in animal models of DMBA-induced
Highlights
Euphorbia tirucalli (L.) is a native plant from Africa known popularly as “avelós” or “pencil tree” and is well adapted to the Brazilian Cerrado biome [1,2]
The aim of the present study was to determine the carcinogenic and/or anticarcinogenic action of the crude latex from E. tirucalli in vivo in a model of carcinogenesis induced by 9,10-dimethyl-1,2-benz-anthracene (DMBA) using histopathological analysis and an immunoassay
The mean body weight of the animals reduced throughout the course of the study
Summary
Euphorbia tirucalli (L.) is a native plant from Africa known popularly as “avelós” or “pencil tree” and is well adapted to the Brazilian Cerrado biome (savanna) [1,2]. The latex from this species is commonly used in traditional medicine [3] for the treatment of cancer [2,4,5,6,7]. The aim of the present study was to determine the carcinogenic and/or anticarcinogenic action of the crude latex from E. tirucalli in vivo in a model of carcinogenesis induced by 9,10-dimethyl-1,2-benz-anthracene (DMBA) using histopathological analysis and an immunoassay. The aim of the present study was to determine the action of crude latex from Euphorbia tirucalli dissolved in DMSO in animal models of DMBA-induced carcinogenesis
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