Abstract
SummaryEffects of copper on red cell glutathione and enzyme levels were investigated in sheep of high- and low-glutathione types. No significant differences were observed in copper induced inhibition of glutathione regeneration or erythrocyte enzyme activities in the two groups of sheep. These results, together with those showing the effect of copper on GSH oxidation suggest that low-glutathione sheep should not be more sensitive to small doses of copper, commonly encountered in chronic copper poisoning in sheep than are high-glutathione sheep.
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