Abstract
Objective To investigate the effect of contoured endoscopic sinus surgery on olfactory function and serum total immunoglobulin E (IgE) level in patients with refractory sinusitis. Methods Eighty patients with refractory sinusitis who were treated in our hospital from April 2018 to May 2019 were randomly divided into control group and observation group, 40 cases in each group. The control group was treated with functional endoscopic sinus surgery (FESS), while the observation group was treated with contoured endoscopic sinus surgery (RSS). The clinical efficacy, olfactory function, and serum total IgE level were compared between the two groups. Results After operation, the total effective rate of the observation group (97.50%) was higher than that of the control group (80.00%), the difference was statistically significant (P<0.05). At 3 months after operation, the olfactory score of the observation group was higher than that of the control group [(6.78±0.96) points vs. (5.15±0.65) points], the total serum IgE level of the observation group was (90.78±10.96) IU/ml, lower than that of the control group [(105.32±12.45) IU/ml], the differences were statistically significant (P<0.05). Conclusion Contoured endoscopic sinus surgery has a significant effect in patients with refractory sinusitis, which can effectively improve the olfactory function of patients and improve serum total IgE level. Key words: Refractory sinusitis; Contoured endoscopic sinus surgery; Olfactory function; Serum total IgE level
Published Version
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