Abstract

Controlled internal drug release (CIDR) devices containing progesterone were used for 16 days to synchronize estrus in 108 mature Spanish does in the natural breeding season. Pregnant mare serum gonadotrophin (PMSG, 250 IU) was given to all does 48 h prior to CIDR removal. At the time of treatment with PMSG, a random half of the does received prostaglandin (PGF, 5 mg dinoprost tromethamine, Lutalyse) to determine the effect of its addition on pregnancy rates and prolificacy in artificially inseminated does. Mean pregnancy rates, 64.5% and 59.5%, and prolificacy, 170% and 166%, were not significantly different ( P>0.05) for does treated with PMSG or PMSG/PGF, respectively. Administering PGF to does on this synchronization regimen in the natural breeding season is unwarranted.

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