Abstract
ABSTRACT 
 In this study the antibacterial effect of cerium oxide nanoparticles(CON) particles on staphylococcus aureus bacteria was investigated. microwave induced technique were used for synthesized cerium oxide nanoparticles. sunthesized Cerium oxide nanoparticles were characterized by Scanning electron microscope (SEM) and X-ray diffraction (XRD) .It was noted that cerium oxide nanoparticles of 18-29 nanometre size were synthesized. XRD and SEM results found that with increasing synthesization time size of cerium oxide nanoparticles were decreased. The size of CON particles was influenced by the time it took to synthesise them.
 It was also found that CON particles antibacterial activity is size dependant.Cerium oxide nanoparticles improved the effectiveness of antibacterial agents in a disc diffusion investigation.With Terivid, Amikin Grasil,velosef, spraxin and ceftriaxone drugs against the staphylococcus aureus bacteria appreciably.
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