Abstract
An increase in the immune reaction towards sheep red cells (SRC) was observed in SRC‐stimulated cultures containing leucocytes from SRC‐immunized rabbits when the leucocyte‐SRC suspensions were centrifuged at high speed before incubation. Immune reaction was also evident in a majority of culture tubes containing purified lymphocytes stimulated with SRC and centrifuged at high speed, while no response was observed in non‐centrifuged tubes. The findings indicate that SRC antigen may stimulate lymphocytes directly without the presence of phagocytes if a close contact is obtained between antigen and reacting cells.
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Schedule a callMore From: Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology
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