Abstract
Aim To compare new remineralizing agents calcium sodium phosphosilicate paste and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste with that of fluoridated toothpaste in remineralization of early carious lesions using scanning electron microscopy and energy-dispersive X-ray (SEM-EDX) analysis.Materials and methods Sixty sound extracted premolars were collected and placed in demineralizing solution for 4 days to produce artificial carious lesions. All specimens were evaluated for any loss of mineral content using SEM-EDX analysis. Samples were randomly assigned to three groups: Group I: Fluoridated toothpaste (control), group II: CPP-ACP paste, and group III: Calcium sodium phosphosilicate paste. Specimens were then treated with above-mentioned remineralizing agents and again measured for mineral content using SEM-EDX analysis.Results Group III (calcium sodium phosphosilicate paste) showed highest significant difference followed in descending order by group II (CPP-ACP paste) and group I (fluoridated toothpaste).Conclusion Calcium sodium phosphosilicate paste showed maximum remineralizing potential compared with CPP-ACP and fluoridated toothpastes.How to cite this article Chaudhary I, Tripathi AM, Yadav G, Saha S. Effect of Casein Phosphopeptide-amorphous Calcium Phosphate and Calcium Sodium Phosphosilicate on Artificial Carious Lesions: An in vitro Study. Int J Clin Pediatr Dent 2017;10(3):261-266.
Highlights
Dental caries is a pathological process of localized destruction of tooth tissue by microorganisms
Group III showed highest significant difference followed in descending order by group II (CPP-ACP paste) and group I
On comparing the calcium and phosphorous concentrations and their ratios in the three study groups after remineralization, results of the present study revealed that mean values of group III were maximum, followed in a descending order by group II (CPP-ACP paste) and group I
Summary
Dental caries is a pathological process of localized destruction of tooth tissue by microorganisms. There are many possibilities to intervene in this continuing process to arrest or reverse the progress of the lesion via remineralization. The noninvasive treatment of early caries lesions by remineralization has the potential to be a major advancement in the clinical management of the disease. The best strategy for caries management is to focus on the methods of improving the remineralizing process with the aid of various remineralization products.[1]. Over the last few decades, fluoride is known to promote remineralization, but is dependent on calcium and phosphate ions from saliva to accomplish this process. Recent investigations have primarily focused on various calcium phosphate-based technologies which are designed to supplement and enhance fluoride’s ability to restore tooth mineral
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