Effect of binding and pinealectomy on photoperiod and seasonal variations in secretion of prolactin in cattle.

Abstract

The role of the eyes and pineal gland on photoperiod- and season-induced changes in secretion of prolactin were studied in male cattle. Increasing exposure to light from 8 to 16 hr each day increased basal and thyrotropin-releasing-hormone-induced secretion of prolactin 3.7- and 4.1-fold in three sham-pinealectomized steers. In contrast, basal and thyrotropin-releasing-hormone-induced increases in secretion of prolactin did not change in four blind bulls and were markedly suppressed in three pinealectomized steers when exposure to light was increased from 8 to 16 hr/day. There was no diurnal variation in secretion of prolactin regardless of photoperiod or surgical treatment. However, seasonal changes (averaged 46 ng/ml in June-Aug vs 7 ng/ml in Dec-Feb) in secretion of prolactin persisted in blind and pinealectomized steers previously shown to be nonresponsive to changing photoperiods. Ambient temperature and photoperiod account for most, but not all, of the seasonal variation in secretion of prolactin. We hypothesize there is an endogenous annual rhythm in the secretion of prolactin in cattle.