Effect of berries/apple mixed juice consumption on the positive modulation of human lipid profile

Abstract

• Consumption of a 50/50% berries/apple juice helped to a positive modulation of lipid profile. • Ingestion of juice led to a reduction of the presence of atherogenic subfractions LDL 3–7. • Bioactive substances present in juice may act as potential non-pharmacological therapeutics of dyslipidemia. • Berries/apple juice contributes for a healthier life-style, possibly decreasing CVDs risk factors. The increased berries consumption is of importance for human health improvement, helping protecting against a number of diseases, especially cardiovascular diseases (CVDs). This study aimed investigating the effect of berries/apple juice consumption on human lipid profile. Healthy volunteers (36 women and 14 men) were instructed to consume 300 mL/day of juice for 21 days. The consumption of juice resulted in a significant decrease of total cholesterol and low-density lipoprotein (LDL) cholesterol levels (only for men group), and significantly increased high-density lipoprotein (HDL) cholesterol and total antioxidant status. Furthermore, atherogenic subfractions LDL3-7 in 5 women and 7 men at the baseline were found, reducing by 0.36 mmol/L (from 0.43 ± 0.19 to 0.06 ± 0.04 mmol/L) and 0.23 mmol/L (from 0.43 ± 0.19 to 0.20 ± 0.09 mmol/L) in the women's and men’s group, respectively. The regular intake of berries/apple juice can be an important strategy to reduce CVDs risk, by positive modulation of the lipid profile and other health attributes in adults.