Abstract
Benzaldehyde (BA) was found to have an inhibitory effect on the proliferation of chemical-transformed rat liver epithelial cells, Culb TC/R/TC. Such cells treated with BA (2 × 10−3 M) ceased proliferation by the 4th or 6th day of cultivation, while control cells continued to proliferate throughout the period (14 days). BA also inhibited the piling-up of cells with no marked morphological change. These effects of BA on cells were seen as temporary and reversible. These data suggested the restoration of the cell-cell contact inhibition to Culb TC/R/TC cells by BA-treatment.
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