Effect of aqueous extract of African mistletoe (<i>Tapinanthus bangwesis</i>) on some serum enzymes of rats with carbon tetrachloride-induced liver damage

Abstract

The in vivo effects of aqueous extract of African mistletoe (Tapinanthus bangwesis) on the serum levels of aspartate and alanine amino transferases (AST and ALT) and alkaline phosphatase (ALP) of Wistar albino rats with carbon tetrachloride-induced liver damage were investigated. The extract was orally administered at 12.5, 25.0 and 37.5 mg/kg body weight 24 hours and every subsequent 48 hours following carbon tetrachloride (CCl4) administration with vegetable oil carrier (1:1) at a dose of 0.5 mg/kg body wt. This study was for three weeks. The results indicated that the serum levels of AST, ALT and ALP reduced significantly (p