Effect of Anesthesia Induction with Midazolam on Hemodynamics in Abdominal Hysterectomy Surgeries

Abstract

Objective: The primary task of anesthesiology is to control the patient's hemodynamic values, including blood pressure and heart rate, from pre-operative to post-operative. Many drugs are used alone or in combination for induction and maintenance of anesthesia. Various hemodynamic responses may develop to these drugs. In our study, we aimed to compare the effects of midazolam and propofol used alone in intravenous anesthesia induction on hemodynamics in patients undergoing abdominal hysterectomy. Materials and Methods: A total of 60 ASA I-II patients scheduled for abdominal hysterectomy were included in the study. During anesthesia induction, midazolam (0.2 mg/kg) was administered to Group M (n:30) and propofol 1% (2 mg/kg) was administered to Group P (n:30). Noninvasive systolic blood pressure, diastolic blood pressure, mean blood pressure and minute heart rate values were recorded. Results: Systolic blood pressure was significantly lower in group P than in M during intubation, skin incision, extubation and recovery. Conclusion:As a result, anesthesia induction with intravenous 0.2 mg/kg midazolam may cause higher systolic blood pressure values than 2 mg/kg propofol. It should not be overlooked that the hemodynamic response that will occur after the use of midazolam during anesthesia monitoring will vary depending on the anesthetic drugs and doses used together.