Abstract
The effect and probable mechanism of action of an aqueous extract of Allium sativum on intestinal motility of the rabbit was studied. Four rabbits were used as experimental animals in this study, and the standard organ bath procedure was used to monitor and record the contractions of the isolated intestine of the rabbits. The effects of acetylcholine, atropine and propranolol were also studied in the presence of the extract in the organ bath. The results show strong correlation between the log concentration of the extract and the percentage relaxation of the ileum, with r = 0.930325. This correlation was highly significant (p Allium sativum decreases intestinal motility in rabbits. KEY WORDS: Allium sativum, garlic, intestinal motility. Nigerian Journal of Health and Biomedical Sciences Vol.4(1) 2005: 40-45
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