Abstract

Objective To observe the efficacy of alphrostadil injection on patients with decompensated cirrhosis. Methods A toatal of 112 patients with decompensated cirrhosis were selected and randomly divided into treatment group and control group, with 56 cases in each group. The patients in control group were treated with conventional liver protection and support treatment, while the patients in treatment group were given alphrostadil injection on the basis of conventional treatment. The changes of liver function index including alanine aminotransferase(ALT), total bilirubin(TBIL), albumin(ALB), prothrombin cativity(PTA), ascites and complications were compared. Results The levels of ALT, TBiL were significant decreased and the levels of ALB, PTA were increased after treatment in both groups(P 0.05). Conclusions Alphrostadil can improve the liver function of patients with liver cirrhosis, it had considerable effects on decompensated cirrhosis. Key words: Alphrostadil; Liver cirrhosis; Liver function

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