Abstract
To evaluate the effect of embryo flash position and movement of the air bubbles at 1 and 60minutes after ET on clinical pregnancy rates (PRs). Prospective clinical trial. University fertility clinic. A total of 230 fresh ultrasound-guided ETs performed by a single physician (C.F.) at the IVF center of Yeditepe University Hospital between September 2016 and February 2017 were included. Transabdominal ultrasonographic guidance at ET. Clinical PRs. There was no significant difference in terms of clinical PRs between women with embryo flash located >15mm and <15mm from the fundus at 1 or 60minutes (P=.6 and P=.7, respectively). The PRs in women with embryo flash located <15mm and >15mm from the fundus were 47% and 60%, respectively (P=.6). The clinical intrauterine PRs were 69.5%, 38.5%, and 19.1% in fundal, static, and cervical, respectively. The highest PR was in fundal when compared with others (P<.01). The clinical PR appears to be associated with the embryo flash movement/migration and the PR was dramatically reduced when the embryo migrated from its original position toward the cervix at 60minutes. We concluded that clinical PR appears to be associated with the embryo flash movement/migration at 60minutes after ET and embryo flash movement toward the fundus is associated with higher clinical PRs. Further well-designed randomized controlled trials are required to optimize ET technique in the future.
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