Abstract
Liver glycogen was determined under standard conditions on intact and adrenalectomized rats with or without adrenocortical adenocarcinoma transplants. Some of these tumor-bearing rats were treated with cortisol acetate before glycogen determination. Liver glycogen was also determined on rats bearing an osteosarcoma or a hepatoma transplant. There was little glycogen deposition in the livers of the hepatoma-bearing rats. Livers of these animals were jaundiced and rats were anemic and did not respond to cortisol. The rats bearing adrenal adenocarcinoma had lower glycogen deposition than the rats bearing osteosarcoma, a non-hormone tumor. This indicates lack of glucocorticoid secretion by this tumor, detectable by liver glycogen deposition. In adrenalectomized rats, animals bearing adrenal adenocarcinoma has lower glycogen deposition than in those without tumors, again indicating lack of glucocorticoid secretion.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
