Abstract

Left ventricular (LV) diastolic filling is determined by multiple factors. 1–4 Recently, diastolic LV filling has been shown to be affected not only by LV diastolic property but also by left atrial filling pressure. 1 Acute blood pressure elevation alters both diastolic LV property and left atrial pressure. 1 In addition, the presence of mitral regurgitation (MR) also affects left atrial pressure 5 and, therefore, LV filling. 4 This study evaluates the effects of acute blood pressure changes on diastolic LV filling characteristics in subjects with and without MR.

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