EFEK ANTIDIARE EKSTRAK ETANOL UMBI RUMPUT TEKI (Cyperus rotundus L.) TERHADAP MENCIT PUTIH

Abstract

ABSTRACT
 Diarrhea is a disease characterized by stimulation of bowel movements continuously and feces that
 are not formed or liquid that has a frequency of more than 3 times in 24 hours. The incidence of
 diarrhea can occur throughout the world and causes 4% of all deaths and 5% of health losses to
 cause disability. Cyperus rotundus L. can be used as an antidiarrheal drug because it contains a
 compound such as tannins and flavonoids. This research is an experimental study with a Post-test
 only Control Group Design. The subjects using white male mice (Mus muscullus) 25 mice and
 divided into 5 groups: positive control, negative control, ethanol extracts of rubers Cyperus
 rotundus L. with a dose of 250 mg/kgBB, 500 mg/kgBB and 1000 mg/kgBB. Before the treatment,
 mice fasted and induced diarrhea (oleum ricini). Obsevations was made by observing the
 parameters of diarrhea: duration of diarrhea, frequency of diarrhea and feces consistency every 30
 minutes for 4 hours. The numerical data was then processed using SPSS with one way ANOVA test.
 The results obtained showed that the administration of extract with a dose of 250 mg/kgBB, 500
 mg/kgBB and 1000 mg/kgBB had an antidarrheal with effective dose is 500 mg/kgBB.
 Keywords: antidiarrheal, ethanol extract of tubers Cyperus rotundus L., oleum ricini, Cyperus
 rotundus