Efeitos dos estimulantes gustativos de secreção salivar e a sua libertação de flúor na saliva

Abstract

ObjectivesTo compare salivary flow stimulation capacity, erosive potential and fluoride quantities released in saliva during the exposure to two different gustatory stimulants of salivary secretion (GSSS). MethodsA double blind randomized controlled trial in cross‐over. Sixty volunteers randomly both recruited and divided into two groups, according to the first GSSS tested. The groups were exposed to GSSS based on citric acid or GSSS containing malic acid, fluoride and xylitol. Unstimulated, mechanical and GSSS stimulated salivary secretions were measured within each group. The pH variations and fluoride release of all samples were measured using potenciometric techniques. Erosive potential was determined regarding salivary pH variations and counts of subjects with pH below 4.5 for over 1min. Results were presented as mean±95% confidence interval and analyzed with Student's t‐test or ANOVA as appropriate and only comparative findings for p<0.05 were accepted. ResultsThe malic acid, fluoride and xylitol GSSS presented an absolute risk reduction (ARR) for potential erosive phenomena's of 13.91% [1.67%; 26.15%] and a number needed to treat (NNT) of 8 when compared with the citric acid GSSS. The same GSSS released 87.75% [81.48%; 94.03%] of the total fluoride quantity announced by the producer into the saliva. ConclusionThe malic acid based GSSS presented similar salivary stimulation efficiency when compared to the GSSS containing citric acid. Moreover the malic acid based GSSS presented a decrease of erosion potential and fluorides release to the saliva, which in turn could potentially protect tooth structure from erosion episodes.